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What Are Probiotics and Prebiotics?

Probiotics are live microorganisms—such as certain bacteria and yeasts—that, when administered in adequate amounts, confer a health benefit by helping maintain a balanced gut microbiome. Common sources include fermented foods like yogurt, sauerkraut, kefir, and kombucha, or as encapsulated supplements.

Prebiotics are the non‐digestible fibers and compounds that “feed” those beneficial microbes. Examples include inulin‐type fructans, galacto‐oligosaccharides, resistant starch, and pectin. Prebiotics occur naturally in plant-based foods (onions, leeks, bananas, garlic) and can also be formulated into functional food ingredients or powder blends.

Together, they help support a diverse and resilient microbiome, which is linked to better digestion, immune function, and overall well‐being.

Key Differences & Manufacturing Considerations

Aspect Probiotics Prebiotics
Function Introduce live beneficial strains Provide substrate for native and added strains
Formulation Requires freeze‐drying, microencapsulation, or enteric coating to ensure viability Stable fiber powders or syrup formats; no viability concerns
Stability & Shelf Life Shelf life typically 12–24 months under controlled humidity/temperature Often 24+ months; hygroscopicity must be managed
Regulatory Must meet live count labeling, purity, and strain identification per FDA/EFSA Must meet dietary fiber or novel ingredient regulations
Quality Control CFU assays, contaminant screening, stability testing Fiber content analysis, moisture/activity monitoring

Manufacturing tip: Co‐formulating probiotics with matching prebiotics (synbiotics) can enhance strain survival and functional benefits—but requires precise moisture control and compatibility testing.

Why Partner with OSM for Your Probiotic & Prebiotic Products?

At Organic Supplement Manufacturing (OSM), we specialize in end-to-end contract manufacturing of high-quality probiotic and prebiotic supplements:

  • Expert Strain Handling: GMP-certified facilities with climate-controlled fermenters and microencapsulation lines.
  • Custom Formulations: Powder blends, sachets, capsules, gummies, and functional foods — all tailored to your brand’s specifications.
  • Regulatory Support: Guidance on FDA New Dietary Ingredient notifications, label claims, and international registrations.

Let OSM help you accelerate time-to-market with turnkey solutions, ensuring your probiotic and prebiotic products meet the highest standards of safety, efficacy, and consumer appeal.

References & Further Reading:

Ready to Partner with a Manufacturer That Cares?

At Organic Supplement Manufacturing, our commitment to personalized service and clear communication sets us apart. If you’re looking for a partner who truly cares about your success, we’re here to help you create high-quality gummies that make an impact.

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