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Microglial Immune State, Nrf2 Hormesis & the Optimal Dose Window

OSM Industry Intel • Summer 2026 The Brain’s Immune Cells Get Stuck in Attack Mode. The Fix Is Not More Antioxidant. It Is the Right Amount. A new Frontiers in Nutrition review reframes neuroprotection around microglial immune state and a dose-response curve that is shaped like an upside-down U. The implication for formulators is uncomfortable […]

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L-Theanine and the Gut-Brain Axis: New Research

OSM Industry Intel • Spring 2026 L-Theanine Has Been Sold as a 30-Minute Ingredient. New Research Says It Is Also Doing Something Much Slower. A new study traces L-theanine’s effects on mood through an unexpected route: the gut microbiome. It reshaped bacterial populations, boosted short-chain fatty acid production, and calmed the same inflammatory pathway in […]

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